Steroids and derivatives
Cayman Chemical 6-MethylmercaptopurIn-d3 10mg
An internal standard for the quantification of 6-MMP by GC- or LC-MS
Medchemexpress LLC Icariside D2 | 38954-02-8 | MFCD29059635 | 1 MG
Icariside D2 is a chemical compound isolated from the Annona glabra fruit. It is known for its ability to inhibit angiotensin-converting enzyme and exhibits a range of biological activities.
- Inhibits angiotensin-converting enzyme
- Shows cytotoxic activity on HL-60 cells with an IC50 value of 9.0 ± 1.0 μM
- Induces apoptosis
- Exhibits anti-inflammatory activity
- Exhibits anti-HIV activity
Cayman Chemical 6-MethylmercaptopurIn-d3 25mg
An internal standard for the quantification of 6-MMP by GC- or LC-MS
Medchemexpress LLC Sulfadoxine-d3 | 1262770-70-6 | MFCD10567357 | 98.0% | 313.35 | C12H11D3N4O4S | 10 MG
Sulfadoxine-d3 is the deuterium-labeled isotopologue of sulfadoxine, a long-acting sulfonamide anti-malarial agent provided as a high-purity analytical standard for research. It is used as an internal standard, tracer, or reference material in pharmacokinetic and mass spectrometry studies.
- Deuterium-labeled analog for tracer and internal standard use.
- High purity, 98.0%, suitable for analytical applications.
- Soluble in DMSO, limited solubility in water.
- Stable as a powder when stored at -20°C, with defined in-solution storage limits.
- Supplied in small analytical quantities useful for method development and validation.
Medchemexpress LLC 1-Methylinosine-d3 (N1-Methylinosine-d3) | 2140-73-0 | 99.0% | 285.27 | 10 MG
1-Methylinosine-d3 is the deuterium-labeled form of 1-Methylinosine. 1-Methylinosine is a modified nucleotide found at position 37 in tRNA, located 3' to the anticodon of eukaryotic tRNA. Deuterium labeling, as seen in this compound, has gained attention for its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- It can be used as a tracer in research applications.
- It serves as an internal standard for quantitative analysis using techniques like NMR, GC-MS, or LC-MS.
- Stable heavy isotopes, such as deuterium, are incorporated into drug molecules for quantitation during drug development.
Medchemexpress LLC Impurity C of alfacalcidol | 82266-85-1 | MFCD22124488 | 99.8% | C35H49N3O4 | 10MG
Impurity C of alfacalcidol is an analytical reference impurity of the vitamin D analogue alfacalcidol, supplied as a high-purity solid for research use. It is intended for impurity profiling, analytical method development, and reference standard applications; follow recommended storage to preserve stability.
- High reported purity of 99.8%.
- Available in small solid quantities including 10 mg.
- Chemical formula C35H49N3O4; molecular weight 575.78.
- Suitable for impurity profiling and method development.
- Store protected from light and under inert atmosphere; in solvent keep at -80°C for long term.
Medchemexpress LLC Guaiacol-d3 | 74495-69-5 | 127.16 | 50 MG
Guaiacol-d3 is the deuterium labeled Guaiacol. Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation. Guaiacol has an anti-inflammatory activity.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Cortodoxone-d2 | 1271728-08-5 | 99.0% | C21H28D2O4 | 1 MG
Cortodoxone-d2 is a deuterium labeled glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone). It is suitable for use as a tracer or an internal standard for quantitative analysis in various analytical techniques.
- Can be used as a tracer.
- Acts as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes as tracers for quantitation in drug development.
- Deuteration offers potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC HY-10001 5mg Medchemexpress, Calcipotriol CAS:112965-21-6 Purity:>98%
Medchemexpress, HY-10001 5mg Calcipotriol CAS:112965-21-6 Calcipotriol is a synthetic VitD 3 analogue with a high affinity for the vitamin D receptor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Dopamine D2 receptor agonist-3 | 1257326-24-1 | 98.3% | 295.81 | C15H22ClN3O | 5 MG
Dopamine D2 receptor agonist-3 is a small-molecule research compound that acts as a selective dopamine D2 receptor partial agonist and a dopamine D3 receptor antagonist, with reported in vitro potency and demonstrated brain penetration in vivo. It is supplied as a solid (white to off-white) with high stated purity for laboratory use.
- Selective D2 partial agonist and D3 antagonist activity.
- Potency reported as pEC50 D2 = 8.3; D3 < 5.5 (approx. D2 EC50 ≈ 5 nM).
- Demonstrated brain penetration (brain:blood ratio 5.5; Tmax 0.5 h at 3 mg/kg, s.c.).
- High purity (98.3%) suitable for research applications.
- Solid, white to off-white appearance, available in small research pack sizes.
Medchemexpress LLC HY-15398 1g Medchemexpress, Vitamin D3 CAS:67-97-0 Purity:>98%
Medchemexpress, HY-15398 1g Vitamin D3 CAS:67-97-0 Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 54668-67-6 | CHOL-5-ENE-3-BETA,24-DIOL | AstaTech360.582 | C24H40O2 | 95.000 | C[C@H](CCCO)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C | 10mg | 722709657
CHOL-5-ENE-3-BETA,24-DIOL | AstaTech | 54668-67-6360.582 | C24H40O2 | 95.000 | C[C@H](CCCO)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C | 10mg | 722709657
Medchemexpress LLC Benzeneacetic acid, α-methyl-4-(2-methylpropyl)-d3, sodium salt (1:1) | 1219805-09-0 | 99.2% | C₁₃H₁₄D₃NaO₂ | 1 MG
This Ibuprofen-d3 sodium product is a white to off-white solid. It exhibits high purity and isotopic enrichment, complying with specified analytical standards.
- Appearance: White to off-white solid
- Purity (HPLC): 99.21%
- Isotopic enrichment: 99.9%
- Recommended storage: 4°C, sealed, away from moisture
- Recommended storage in solvent: -80°C for up to 6 months; -20°C for up to 1 month, sealed and away from moisture
Medchemexpress LLC Melatonin-d3 (N-acetyl-5-methoxytryptamine-d3) | 90735-69-6 | 99.2% | C13H13D3N2O2 | 1 MG
Melatonin-d3 is a deuterium-labeled form of Melatonin, a hormone produced by the pineal gland. Melatonin activates melatonin receptors and is known for its role in sleep, as well as its significant antioxidative and anti-inflammatory properties. It has been identified as a novel selective ATF-6 inhibitor and can induce apoptosis in human hepatoma cells by downregulating COX-2. Additionally, Melatonin has been shown to attenuate palmitic acid-induced mouse granulosa cell apoptosis through endoplasmic reticulum stress.
- Deuterium labeled
- Tracer
- Internal standard for quantitative analysis
- Pharmacokinetic studies